Perspectives on Ion Permeation
نویسندگان
چکیده
منابع مشابه
Letter to the Editor Forces Determining Ion Permeation
I would like to address two key issues related to the Perspectives on Ion Permeation . The first is the estimate of the size of the physical forces relevant for ion transport. Any good physical model of ion permeation requires the identification of the dominant forces. The second subject concerns a careful definition of the terms “mean field” and “mean field approximation.” Several articles in ...
متن کاملForces Determining Ion Permeation
I would like to address two key issues related to the Perspectives on Ion Permeation . The first is the estimate of the size of the physical forces relevant for ion transport. Any good physical model of ion permeation requires the identification of the dominant forces. The second subject concerns a careful definition of the terms “mean field” and “mean field approximation.” Several articles in ...
متن کاملPermeation in ion channels: the interplay of structure and theory.
Combined with high-resolution atomic-level crystal structures of channel forming peptides, theory has become a powerful tool for illuminating factors influencing permeation. Here, advantages and limitations of the more familiar continuum and molecular modeling techniques are briefly outlined. These methods are applied to issues of permeation in two different channel families: gramicidin and K(+...
متن کاملTheories of Ion Permeation
The Perspectives on Ion Permeation in the June issue of The Journal of General Physiology provided a unique exposition of contrasting views regarding kinetic rate models, electrodiffusions, Brownian dynamics, and PoissonNernst-Planck (PNP). The debate is timely, healthy, and desirable, because recent progress in the determination of the three-dimensional structure of biological ion channels at ...
متن کاملA mesoscopic approach to understanding the mechanisms underlying the ion permeation on the discrete-state diagram
a broad range of per-meation events from femtoseconds to minutes in time scale and sub-angstrom to millimeter in space were discussed. A main message in the Perspectives was to explore each discipline to expand its limitation, such that different levels of knowledge in a hierarchy of ion permeation events are integrated. Here, we propose another approach from a mesoscopic point of view. Electro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 1999